The aim of this study to investigate methodological aspects that may affect glycemic index (GI) and insulinemic (II) values. In addition, we will measure GI and II values for typical Finnish carbohydrate-rich foods and provide a database of GIs for Finnish foods. The specific aims of this study are: * to compare glycemic responses and GIs analyzed from capillary and venous blood to compare glucose against white bread as the reference food, and to study the effect of number of reference tests on GI values. For each setting of the tested parameters, we determined the glycemic indices of rye bread, oatmeal porridge and instant mashed potato * to examine the glycaemic and insulinaemic responses of a mashed potato-based meal when a high fat food (rapeseed oil) or a high protein food (chicken breast) or fat, protein and salad together were added to the meal. Furthermore, we studied how the predicted and measured GI values of the mixed meal differed from each other. * to examine the effects of two different coffee portions with glucose and caffeine-containing soft drinks on postprandial glucose and insulin responses. Further objectives were to study how coffee and different accompaniments affect glucose and insulin responses. * to measure GI values for typical Finnish foods * to study the effects of berries on glycemic and insulinemic responses * to examine the effects of overweight and glucose tolerance on the glucose, insulin and lipid responses to an HGI meal and an LGI meal.Furthermore, the second aim was to study the effect of BMI and glucose tolerance on the GI measured. * to compare methodological choices in insulin measurement * to investigate the effect of alcohol on postprandial glucose and insulin responses, and to determine glycemic and insulinemic indices values for beer and non-alcoholic beer
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
142
Measuring GI and II values for Finnish foods
Glucose
Area under the plasma concentration versus time curve (AUC) of food
Time frame: 2 to 5 hours
Insulin
Area under the plasma concentration versus time curve (AUC) of food
Time frame: 2 to 5 hours
Free fatty acids
Area under the plasma concentration versus time curve (AUC) of food
Time frame: 2 to 5 hours
Triglyserides
Area under the plasma concentration versus time curve (AUC) of food
Time frame: 2 to 5 hours
IGF1
Area under the plasma concentration versus time curve (AUC) of food
Time frame: 2 to 5 hours
Satiety
Satiety scores on the satiety scale
Time frame: 2 to 5 hours
IGF-BP1
Area under the plasma concentration versus time curve (AUC) of food
Time frame: 2 to 5 hours
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