The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency Department

Overview

The purpose of this study is to evaluate the anti-emetic effect of oral ondansetron. For this evaluation, the investigators will perform a multi-center, double-blind, placebo-controled, randomized study. The investigators assumption is that oral ondansetron prior to intramuscular ketamine will reduce the occurrence of ketamine-induced vomiting.

Methods * a multi-center, double-blind, placebo-controled, randomized study ( 4 tertiary hospital ED) * survey for the occurrence of vomiting at ED and after discharge Primary outcome * the number of vomiting at ED and at home Secondary outcome * parent's satisfaction and ED length of stay

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Central Contacts