Study of Reduced Anti-coagulation/Anti-platelet Therapy in Patients With the HeartMate II Left Ventricular Assist System (LVAS) (TRACE)

Inclusion Criteria: * HeartMate II Left Ventricular Assist Device (LVAD) patient * Patient has signed an informed consent for data collection. * Patient was discharged, or is being discharged, from the hospital after their initial LVAD implant surgery. * Patient: * at time of enrolling in study, is currently on, with the intention of being maintained on reduced anti-thrombotic therapy (RT) for chronic long-term management. OR \-- On or after January 1, 2011 patient was being maintained on, or had been initiated with the intention of being maintained on, reduced anti-thrombotic therapy (RT) for chronic long-term management; but where RT was subsequently discontinued due to an adverse event or transplant, explant, or death. Exclusion Criteria: * Patients under acute management of anti-thrombotic agents before a final decision on long term antithrombotic strategy. * Patients requiring a legal representative to sign consent form, rather than themselves. * Patient is being managed on other anti-thrombotic agents