Prospective Dengue Seroprevalence Study in 5 to 10 Year-old Children

Sanofi Pasteur, a Sanofi Company667 enrolled

Overview

This is a descriptive prospective community-based seroprevalence study. Primary objective: * To determine the prevalence of specific antibodies (immunoglobulin G \[IgG\]) against dengue in healthy 5 to 10 year-old children in India. Secondary objectives: * To determine the dengue virus serotype (DeNV-1,2,3 and /or 4) specific to the antibodies in positive (IgG) samples * To estimate the prevalence of specific antibodies (IgG) against Japanese encephalitis in healthy 5 to 10 year-old children in India.

Study Type

OBSERVATIONAL

Enrollment

667

Conditions

Dengue Dengue Fever Dengue Hemorrhagic Fever

Eligibility

Sex: ALLMin age: 5 YearsMax age: 10 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Aged between 5 and 10 year-old on the day of inclusion * Healthy child as reported by the parent or legally qualified guardian * Being registered in selected study site * Provision of the informed consent form signed by at least one parent or legally qualified guardian * For children between 8 and 10 years old, provision of the assent form signed. Exclusion Criteria: * N/A

Locations (4)

Unnamed facility

Kalyani, West Bengali, India

Unnamed facility

Bangalore, India

Unnamed facility

Hyderabad, India

Unnamed facility

New Delhi, India

Outcomes

Primary Outcomes

Prevalence of positive samples with dengue specific serotype DENV 1, 2,3 and/or 4

Time frame: Baseline

Secondary Outcomes

Prevalence of positive serum samples with JEV specific IgG antibodies

Time frame: Baseline