Safety Study of Group A, C, Y & W-135 Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine for Meningitis

Inclusion Criteria: * Willing and able to give informed consent and comply with all aspects of the evaluation after the nature of the study is explain * For the purpose of this study, a healthy volunteer is defined as healthy male or female, with no significant chronic conditions * Age 18 to 50 years old * Either gender. Abstinence or use of contraception during the eight weeks after vaccination will be required for non menopausal (\< two years post-menopause) or non surgically sterile women * Persons with antibody titer(s) of \<2 µg/mL to serogroup(s) A, C, Y, or W-135 polysaccharides as measured by ELISA Exclusion Criteria: * Age less than 18 years or over 50 years. * History of Guillain-Barré syndrome (GBS). * Pregnancy or lactation. * History of meningococcal meningitis. * History of invasive (clinical or laboratory diagnosis) meningococcal disease. * History of meningococcal meningitis vaccination. * Screening laboratory abnormalities (in the opinion of the Investigator) that would raise safety concerns for participation in the study. * Use of immunosuppressive drugs within 30 days prior to study enrollment, not including topical or inhaled steroids/cytotoxic agents. * History of anaphylactic shock, asthma, urticaria, or other allergic or hypersensitivity reactions following vaccination. * History of severe allergic disorders or autoimmune connective tissue disorders, including rheumatoid arthritis. A high sensitivity C-Reactive Protein (CRP) test at screening will be used as part of the assessment of autoimmune disorders by the Principal Investigator. * Use of systemic antibiotics within 72 hours prior to study enrollment. * History of cirrhosis. * Positive results of testing for HepBsAg, Hepatitis C or HIV-1 or HIV-2 antibodies. * Positive results of drug screen (amphetamine, THC, cocaine). * Persons with antibody titer(s) of \>2 µg/mL to serogroup (s) A, C, Y, or W 135 as measured by ELISA. * Unable to understand all of the study requirements. * Prisoners. * Participation in a clinical trial in the last three months. * History of any serious chronic medical or psychiatric illnesses. * History of significant head trauma, alcohol or substance abuse or other medical illnesses that could cause a neurological deficit (e.g., cerebro-vascular disease) . * Chronic medication use that, in the opinion of the Investigator, may influence or bias the clinical outcome of the trial. * Individuals will be excluded from participation in this trial if they are judged by the Principal Investigator as having a significant impairment in their capacity for judgment or reasoning that compromise their ability to make decisions in their best interest.