Intelligence Changes Following Minor Surgery

RenJi Hospital

Overview

Animal studies showed that many general anesthetics might result in neuron apoptosis and neurocognitive impairment in the developing brain. However results from human studies are conflicted. In present study, the investigators examined the association between early exposure to anesthesia and surgery for minor surgery and intelligence changes in adolescence using the Wechsler Intelligence Scale for Children.

Study Type

OBSERVATIONAL

Conditions

Hypospadia Phimosis Inguinal Hernia

Eligibility

Sex: MALEMin age: 6 YearsMax age: 16 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Born from 1995 2. Male 3. Parents or guardian agree to attend this study 4. Undergone minor surgery (Repair of hypospadias, phimosiectomy, cryptorchidectomy or cryptorchidopexy and repair of inguinal hernia) 5. Children who scarify the No.1 to No.3 but no experience of any surgery. 6. Those who undergone minor surgery in Renji Hospital 4-6years ago. Exclusion Criteria: 1. Any congenital central nervous system diseases 2. Any congenital heart diseases 3. Any congenital dysgnosia 4. Birth weight less than 2kg 5. Ever been hypoxic encephalopathy when birth

Locations (1)

Renji Hospital

Shanghai, China

Outcomes

Primary Outcomes

Wechsler Intelligence Scale for Children

Wechsler Intelligence Scale for Children will be done after surgery, the expected average of 5 years after surgery.

Time frame: Average 5 years after surgery

Secondary Outcomes

Achenbach Child Behavior Checklist

Wechsler Intelligence Scale for Children will be done after surgery, the expected average of 5 years after surgery.

Time frame: Average 5 years after surgery

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.