Environmental factors may play a role in the genesis of pulmonary hypertension, especially in endothelial dysfunction. One widespread environmental factor associated with systemic endothelial dysfunction is cigarette smoke. It may well be that cigarette smoking is not only a risk factor for systemic but also for pulmonary vascular diseases and herewith may interact with other risk factors such as a genetic background and associated conditions. The existing studies which deal with this subject are only small single center case control studies providing less data. Therefore a large European multicenter study is necessary. The investigators hypothesis are: * a history of tobacco smoke exposure is highly prevalent in patients with PAH compared to the unaffected general population. * a history of tobacco smoke exposure is more prevalent in patients with PAH compared to CTEPH.
Study Type
OBSERVATIONAL
Enrollment
500
University Hospital of Graz
Graz, Austria
University Hospital of Innsbruck
Innsbruck, Austria
University Hospital Dresden
Dresden, Germany
University of Greifswald
Greifswald, Germany
University Hospital of Heidelberg
Heidelberg, Germany
University hospital of Homburg
Homburg, Germany
University Hospital of Regensburg
Regensburg, Germany
University Hospital of Würzburg
Würzburg, Germany
University Hospital Zurich
Zurich, Switzerland
Difference in Prevalence of Smoking history in patients with PAH compared to unaffected general population
Patients will be asked with a specific questionnaire concerning their tobacco smoke exposure and smoking history. Control-group: Data from Swiss health survey (SHS) 2007 (Gesundheitsbefragung Schweiz).
Time frame: Assessment during outpatient consultation, an expected average of 1 day.
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