A Multiple Ascending Dose Study of ETC-1002 in Healthy Subjects

Major Inclusion Criteria: * Healthy male and female subjects of non-child bearing potential as determined by medical history, physical exam and vial sign measurements * Body Mass Index of 18-32 kg/m2 inclusive with body weight \>50 kg Major Exclusion Criteria: * Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \>1.2 x Upper Limit of Normal(ULN), serum creatinine \>ULN, Hemoglobin \<12.0 g/dL * Clinically significant disease that requires a physician's care and/or would interfere with study evaluations * History of drug or alcohol abuse, consumption of alcohol within 48 hours prior to randomization, or a positive test for alcohol or drugs with a high potential for abuse prior to randomization * Use of any prescription or nonprescription drugs, vitamins, or dietary supplements within 14 days prior to randomization * Other exclusion criteria apply