Adjuvant Chemotherapy in Patients With Lymph Node Metastasis After Radical Surgery in Cervical Cancer

Korean Gynecologic Oncology Group69 enrolled

Overview

Purpose Primary endpoint * To evaluate the 3-year disease free survival Second endpoints * To evaluate the 3-year \& 5-year overall survival To analyze the toxicity and the quality of life

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Cervical Cancer

Interventions

paclitaxelDRUG

Paclitaxel 175 mg/m2 over 3 hr Repeat every 3 weeks \* 6 cycles

Cisplatin 50mg/m2DRUG

Cisplatin 50mg/m2 Repeat every 3 weeks \* 6 cycles

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * cervical cancer stage Ia2-IIa * histology; squamous, adeno, adenosquamous subtype * age; 20∼70 years * performance status; GOG 0∼2 * no medical illness * hematologic, renal, hepatic function; normal * grossly no residual disease * histologically confirmed lymph nodes metastases * no parametrial extension and negative resection margin * number of retrieved lymph nodes; ≥ 20 Exclusion Criteria: * patients with grade 2 peripheral neuropathy * patients with uncontrolled infection

Locations (1)

KGOG

Seoul, South Korea

RECRUITING

Outcomes

Primary Outcomes

Kaplan-Meier

Secondary Outcomes

log-rank test Cox regression analysis

Central Contacts

Eunkyung Park

CONTACT

8225125420 koreagynonco@gmail.com

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.