Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma

Technische Universität Dresden44 enrolled

Overview

The purpose of the study is to prove if there is any difference in the nerve fiber layer between patients with normal- and high-tension-glaucoma with similar structural optic nerve head parameters.

It is till now not definitely clear whether normal- and high-tension glaucoma are different forms of the same disease and whether they have similar pathogenetic mechanisms. Spectral domain optical coherence tomography (SD-OCT) is supposed to objectively evaluate retinal nerve fiber layer (RNFL) thickness. The investigators propose a study to compare the RNFL in patients with normal- and high-tension-glaucoma. In order to exclude other possible differences,which could influence the results, only patients with similar structural optic nerve head damage in both groups will be compared.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Normal Tension Glaucoma High Tension Glaucoma

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * persons over 18 years * men or women * with normal- and high-tension glaucoma Exclusion Criteria: * cataract * cloudy cornea and other conditions with bad visualisation quality of optic nerve head * optic nerve atrophy except glaucomatous

Outcomes

Primary Outcomes

RNFL in different segments

RNFL in upper, lower, temporal and nasal segments

Time frame: up to 9 Months

Data from ClinicalTrials.gov

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