Objective 1: Determine if Vitamin D supplementation can improve body composition, reduce injuries and illnesses, and improve performance in collegiate swimmers and divers. Objective 2: Examine how baseline Vitamin D levels predict outcome variables over the course of the intervention period.
The investigators plan to recruit from approximately 45 male and female University of Kentucky Swimmers and Divers, at least 18 years of age in August 2011. Approximately equal numbers of men and women will be recruited. The entire athletic team(s) will be recruited. With a conservative dropout rate of 30%, the investigators final sample size should be approximately 22 participants (per group).Following baseline measures, participants will be randomized to one of two groups (Vitamin D 4000 IU or Placebo control) and monitored over the course of their athletic season. Measurements will be repeated at Midpoint (3 months) and Endpoint (6 months). Participants will have no recent history of Vitamin D supplementation beyond what is normally found in a multivitamin (400 IUs). Following the informed consent process a medical history and Vitamin D questionnaire (screenings), and urine pregnancy test (for female athletes) will be administered prior to more invasive baseline testing procedures (blood draw and DXA). A blood draw will then be conducted at baseline, midpoint and endpoint. Collected blood for the purposes of this study will assess Vitamin D status (25(OH)D), parathyroid hormone, ionized calcium, bone turnover markers, and inflammatory cytokines. A Vitamin D lifestyle questionnaire will be administered at all 3 time points and incidence of illness and injury will be documented over 6 months following randomization. DXA measures will only occur at Baseline and Endpoint.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
QUADRUPLE
Enrollment
45
University of Kentucky
Lexington, Kentucky, United States
25(OH)D)
Baseline, Midpoint, and Endpoint measures include a blood draw for 25(OH)D status.
Time frame: 3 measurement periods over 6 months
Inflammatory Cytokines
Baselineand Endpoint measures include a blood draw inflammatory cytokines (TNF alpha, IL1-B, IL6)
Time frame: Baseline and Enpoint
Bone Turnover Markers
Baseline, Midpoint, and Endpoint measures include a blood draw for bone turnover markers (BSAP, NTx).
Time frame: Baseline, Midpoint, Endpoint
DXA Body Composition
Baseline and Endpoint measures include Body Composition measures (DXA) for fat, muscle and bone composition
Time frame: Baseline and Endpoint
Vitamin D Lifestyle Survey
Baseline, Midpoint, and Endpoint measures include a behavioral survey for estimating 25(OH)D status (solar exposure, food and other supplemental intake)
Time frame: Baseline, Midpoint, Endpoint
injury and illness incidence
We will track injury and illness type and incidence over the course of the 6 month intervention
Time frame: 6 months
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