The primary objective of this investigation is to determine the relative percentage and rate of incorporation of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and total omega-3 (n-3) fatty acids after ingestion of 4 emulsified flavored triglyceride fish oil supplements versus an encapsulated triglyceride in defined plasma lipid pools. The primary endpoints to be evaluated include the fatty acid composition of plasma lipids before and after consumption of a single dose of emulsified triglyceride based fish oil and triglyceride of similar n-3 compositions in capsule form. The investigators will measure changes in plasma phospholipid, and chylomicron fatty acids.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
19
660 mg EPA, 434 mg DHA
660 mg EPA, 436 mg DHA
660 mg EPA, 660 mg DHA
660 mg EPA, 440 mg DHA
USDA Grand Forks Human Nutrition Research Center
Grand Forks, North Dakota, United States
Area under the curve for phospholipid fatty acids
Evaluation of the bioavailability of fatty acids from fish oil supplements
Time frame: 48 hours
Area under the curve for chylomicron fatty acids
Evaluation of the bioavailability of fatty acids from fish oil supplements
Time frame: 48 hours
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