Inhibitory Receptors in Eosinophils of Atopic Subjects

Meir Medical Center40 enrolled

Overview

The purpose of this study is to analyze the expression and activity of inhibitory molecules on eosinophils obtained from allergic subjects.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Atopy Atopic Dermatitis Asthma Allergic Rhinitis Food Allergy

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age 20-60 years * a physician-diagnosed atopic disease Exclusion Criteria: * atopic disease not active * steroid treatment * active non-atopic inflammatory disease, including infections * pregnancy

Locations (1)

Meir Medical Center. Unit of Allergy and Clinical Immunology

Kfar Saba, Israel

Outcomes

Primary Outcomes

Expression of surface molecules on eosinophils as assessed by flow cytometry

Blood samples from donors will be stained and evaluated by flow cytomtery

Time frame: December 2013

Data from ClinicalTrials.gov

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