Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Somatropin Produced by Laboratory Blausiegel Indústria e Comércio Ltda., Compared to Saizen® From Laboratory Merck Serono S.A.

Inclusion Criteria: 1. Research subjects who agree with all study procedures, sign and date, of their own free will, the IC; 2. Research subjects were male, aged between 18 and 32 years; 3. Research subjects with body mass index greater than or equal to 20 and less than or equal to 25; 4. Considered healthy subjects, both clinical and laboratory. Exclusion Criteria: 1. Have donated or lost 450 mL or more blood in the 6 months preceding the study; 2. Having participated in any experimental study or have taken any experimental drug in the 12 months preceding the start of the study; 3. Having made use of regular medication less than two weeks to interfere with the pharmacokinetics / pharmacodynamics of the drug under study, such as glucocorticoids, anabolic steroids, androgens, estrogens and thyroid hormones; 4. Present history of alcohol abuse, drug or drugs; 5. Have a history of liver disease, renal, pulmonary, gastrointestinal, hematologic, or psychiatric; 6. Have made previous use of somatropin; 7. Make use of energy supplements and / or be frequent consumers of soy products (eg replacement of animal milk for soy milk).