Effects of Different Coffee Amounts on Energy Intake, Appetite, Glucose Metabolism and Inflammatory Markers

Harokopio University33 enrolled

Overview

The purpose of the study is to investigate whether different doses of caffeinated coffee consumption has acute effects on subjective appetite feelings, energy intake and biochemical markers related to appetite, inflammation and glucose metabolism compared to water consumption in normal weight and overweight/obese participants.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Obesity Inflammation

Interventions

coffeeOTHER

Comparison of different amounts of coffee

Eligibility

Sex: ALLMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * apparently healthy * habitual coffee drinkers (\>= 1cup of coffee/day) Exclusion Criteria: * smokers * restrained eaters (as this was evaluated using the Dutch Eating Behaviour Questionnaire) * those who reported slimming or any other dietary regime * athletes * participants with a known diagnosis of either hypertension, diabetes, impaired glucose tolerance or a fasting blood glucose concentration above 125 mg/dl * subjects on medication for hypertension or on medication known to alter glucose metabolism * subjects who were on medication that may have an impact on appetite and sensory functioning or who reported a metabolic or * endocrine disease, * gastrointestinal disorders, * a history of medical or surgical events that may have affected the study outcomes

Locations (1)

Metabolic Unit of the Department of Nutrition and Dietetics, Harokopio University

Athens, Greece

Outcomes

Primary Outcomes

energy intake ad libitum

Time frame: 180 min after breakfast/drink consumption

total energy intake

Time frame: One day

appetite feelings

Time frame: fasting (-15 min)

appetite feelings

Time frame: immediately after breakfast/drink consumption (0 min)

appetite feelings

Time frame: 15 min after breakfast/drink consumption

appetite feelings

Time frame: 30 min after breakfast/drink consumption

appetite feelings

Time frame: 60 min after breakfast/drink consumption

appetite feelings

Time frame: 90 min after breakfast/drink consumption

appetite feelings

Time frame: 120 min after breakfast/drink consumption

appetite feelings

Time frame: 150 min after breakfast/drink consumption

appetite feelings

Time frame: 180 min after breakfast/drink consumption

appetite hormones

Time frame: fasting (-15 min)

appetite hormones

Time frame: immediately after breakfast/drink consumption (0 min)

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.

appetite hormones

Time frame: 15 min after breakfast/drink consumption

appetite hormones

Time frame: 30 min after breakfast/drink consumption

appetite hormones

Time frame: 60 min after breakfast/drink consumption

appetite hormones

Time frame: 90 min after breakfast/drink consumption

appetite hormones

Time frame: 120 min after breakfast/drink consumption

appetite hormones

Time frame: 150 min after breakfast/drink consumption

appetite hormones

Time frame: 180 min after breakfast/drink consumption

markers of inflammation

Time frame: fasting (-15 min)

markers of inflammation

Time frame: immediately after breakfast/drink consumption (0 min)

markers of inflammation

Time frame: 15 min after breakfast/drink consumption

markers of inflammation

Time frame: 30 min after breakfast/drink consumption

markers of inflammation

Time frame: 60 min after breakfast/drink consumption

markers of inflammation

Time frame: 90 min after breakfast/drink consumption

markers of inflammation

Time frame: 120 min after breakfast/drink consumption

markers of inflammation

Time frame: 150 min after breakfast/drink consumption

markers of inflammation

Time frame: 180 min after breakfast/drink consumption

markers of glucose metabolism

Time frame: fasting (-15 min)

markers of glucose metabolism

Time frame: immediately after breakfast/drink consumption (0 min)

markers of glucose metabolism

Time frame: 15 min after breakfast/drink consumption

markers of glucose metabolism

Time frame: 30 min after breakfast/drink consumption

markers of glucose metabolism

Time frame: 60 min after breakfast/drink consumption

markers of glucose metabolism

Time frame: 90 min after breakfast/drink consumption

markers of glucose metabolism

Time frame: 120 min after breakfast/drink consumption

markers of glucose metabolism

Time frame: 150 min after breakfast/drink consumption

markers of glucose metabolism

Time frame: 180 min after breakfast/drink consumption

Secondary Outcomes

% carbohydrates ad libitum

Time frame: 180 min after breakfast/drink consumption

% carbohydrates total day

Time frame: One day

% protein ad libitum

Time frame: 180 min after breakfast/drink consumption

% protein total day

Time frame: One day

% fat

Time frame: 180 min after breakfast/drink consumption

% fat total day

Time frame: One day