Manual Therapy on the Improvement of Functional Disability in Patients With Chronic Non Specific Low Back Pain

University of Applied Sciences of Western Switzerland42 enrolled

Overview

Background: Models have tried to explain the driving mechanisms behind chronic non specific low back pain (CNSLBP) in order to propose better appropriate conservative treatment. Altered responses at spinal and/or supraspinal level may affect the perception of pain and degree of disability of CNSLBP patients. Recent clinical recommendations still propose active exercises (AE) for CNSLBP. However, acceptance of exercises by patients may be limited by pain-related manifestations. Current evidences suggest manual therapy (MT) induces a short-term analgesic effect through neurophysiological mechanisms at peripheral, spinal and cortical levels. The aim of this study was first, to assess whether MT has an instant analgesic effect, and second, to compare the long-lasting effect on functional disability of MT followed by AE to sham therapy (ST) followed by AE. Methods: Forty-two CNSLBP patients without co-morbidities, randomly distributed into 2 treatment groups, received either spinal manipulation/mobilization (first intervention) plus AE (MT group; n = 22), or detuned ultrasound (first intervention) plus AE (ST group; n = 20). Eight therapeutic sessions were delivered over 4 to 8 weeks. Instant analgesic effect was obtained by measuring pain intensity (Visual Analogue Scale) before and immediately after the first intervention of each therapeutic session. Pain intensity, disability (Oswestry Disability Index) and fear-avoidance beliefs (Fear-Avoidance Beliefs Questionnaire) were determined before treatment, after the 8th therapeutic session, and at 3- and 6-month follow-ups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Interventions

Manual therapy and active exercisesPROCEDURE

Spinal manipulation/mobilisation (5-10 minutes), consisting of passive accessory intervertebral movements, muscle-energy techniques and high velocity, low amplitude dynamic thrust. Active exercises (20 minutes), consisting of mobility, stretching, strengthening and motor control exercises

Detuned ultrasound and active exercisesPROCEDURE

Electrotherapy device inactivated and ineffective. Active exercises, consisting of mobility, stretching, strengthening and motor control exercises

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * suffering from non specific low back pain with or without symptoms in the lower extremity for a period between 12 and 26 weeks * can maintain the usual medication Exclusion Criteria: * spinal fracture or surgery within the previous 6 months * pregnancy * neoplasia * spinal infection * spinal inflammatory arthritis * low back pain of visceral origin * severe sensitive and/or motor radicular deficit from nerve root origin of less than 6 months * score of 3/5 or more on the Waddell Score * on sick leaves from work for 6 months or more * psychiatric disorders * opioid medication * patient unable to collaborate (linguistic barrier; cognitive impairments) * radiologic abnormalities other than degenerative disease * clinical neurogenic claudication.

Outcomes

Primary Outcomes

Visual Analogue Scale - VAS-pain

self-report of clinical pain intensity, consisting of a 10 cm horizontal line scale on which is added the statements "no pain" on the left and "maximum intensity of pain" on the right

Time frame: During treatment, over a period of 4 to 8 weeks

Secondary Outcomes

Fear-avoidance beliefs (Fear-Avoidance Beliefs Questionnaire - FABQ)

measures level of fear and avoidance beliefs about work and physical activity in patients with low back pain

Time frame: Before randomization and untill 6 months after the end of treatment