Effect of Cocoa Consumption in Cardiovascular and Immune Parameters

Universidad de Antioquia69 enrolled

Overview

Arterial hypertension is one of the most preventable risk factors for stroke, cardiovascular and renal disease. Cocoa is rich in a subclass of flavonoid called flavanol this increase nitric oxide production and is involved in controlling blood pressure.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Arterial Hypertension

Interventions

Dark chocolateDIETARY_SUPPLEMENT

Each chocolate bar provided 210 calories represented in 25 grams of carbohydrates, 3 g of proteins, 18 g of total fat and the presence of 70% cocoa solids

White chocolateDIETARY_SUPPLEMENT

Each chocolate bar provided 230 calories represented in 28 grams of carbohydrates, 3 g of proteins, 18 g of total fat, without the presence of 70% cocoa solids

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age: 18 - 65 years old * Resides in Medellín City * Attached from the contributive regimen of Colombian Health System * Essential Arterial Hypertension, stage I. Diagnosis less than 3 months. * Medically indicated non-pharmacological therapy. * Voluntary desire to consume 50 grams of chocolate per day for 12 weeks. * Voluntary desire to participate in the trial and sign informed consent. Exclusion Criteria: * Suspect of secondary hypertension * Suspect of injury in target organ * Presence of diabetes mellitus * BMI (Body Mass Index) major or equal to 30 * Present smoker or with less than four weeks of abstinence of tobacco * Consume antiplatelet substances * Regular consumption of antioxidants, multivitamins, anti-inflammatory medications, drugs for nasal congestion and sibutramine

Locations (1)

Sede Investigaciones Universitarias, Universidad de Antioquia

Medellín, Antioquia, Colombia