Biomarkers in Tumor Tissue Samples From Younger Patients With Rhabdomyosarcoma

Children's Oncology Group77 enrolled

Overview

This research trial studies biomarkers in tumor tissue samples from younger patients with rhabdomyosarcoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer

PRIMARY OBJECTIVES: I. To demonstrate CRKL expression at the protein level in rhabdomyosarcoma tumors by tissue microarray (TMA). OUTLINE: Archived tumor tissue samples are analyzed for CRKL expression.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Alveolar Childhood Rhabdomyosarcoma Childhood Rhabdomyosarcoma Embryonal Childhood Rhabdomyosarcoma

Interventions

laboratory biomarker analysisOTHER

Correlative studies

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Alveolar rhabdomyosarcoma and embryonal rhabdomyosarcoma specimens from the Children Oncology Group (COG) tumor microarrays (TMAs)

Locations (1)

Children's Oncology Group

Monrovia, California, United States

Outcomes

Primary Outcomes

CRKL expression at the protein level

Time frame: 1 month

Data from ClinicalTrials.gov

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