Pharmacokinetics, Safety, and Tolerability of TR-701 Free Acid (FA) in Elderly Subjects

Inclusion Criteria: * Male or female subjects in the following groups: An elderly subject at least 65 years of age. At least 5 subjects must be at least 75 years of age OR A matched-control subject between 18 and 45 years of age, inclusive * BMI ≥18.0 kg/m2 and ≤35.0 kg/m2 Elderly Group * Medical history, physical examination, and laboratory results consistent with stable health (as determined by the Investigator) Control Group * Medically stable with no clinically significant abnormalities Exclusion Criteria: * Significant, uncontrolled, or life-threatening condition or organ or system condition or disease (eg, impaired cognitive status, respiratory insufficiency, advanced malnutrition) * Positive hepatitis B surface antigen, hepatitis C virus antibody, or human immunodeficiency virus antibody test result * Previous inclusion in a TR-701 FA or TR-701 clinical study * ECG finding of QTc interval \>500 msec, or other clinically significant ECG abnormality at Screening * Female subjects whom are pregnant, lactating or breastfeeding