The purpose of this study is to evaluate if treatment with vitamin D increase beta cell function and insulin sensitivity in subjects with pre-diabetes or newly diagnosed diabetes mellitus type 2.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
44
Oral drops 30000 IU weekly
Matching placebo
Dpt of Endocrinology, Karolinska University Hospital
Stockholm, Stockholm County, Sweden
Beta cell function
Assessed by hyperglycemic clamp investigation
Time frame: 8 weeks
Insulin sensitivity
Assessed by hyperglycemic clamp investigation
Time frame: 8 weeks
Glucose tolerance
Assessed by OGTT
Time frame: 8 weeks
Hypercalcemia
Time frame: 8 weeks
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