Effect of Vitamin D3 on Cardiovascular Risk Factors

N/ACompletedNCT01501916

Martin-Luther-Universität Halle-Wittenberg250 enrolled

Overview

The aim of this study is to investigate whether a supplementation of Vitamin D3 can be used to reduce atherosclerotic risk factors.

It is the objective of this study to investigate whether a supplementation with Vitamin D3 can be used to reduce atherosclerotic risk factors such as hypertension, inflammation and hyperlipidemia. The research question is whether Vitamin D3 can lower blood pressure in mildly hypertensive subjects who are naive to antihypertensive medication, whether Vitamin D reduces the level of systemic inflammation and whether Vitamin D3 has an effect on blood lipids. major outcomes: \- decrease of systolic blood pressure in the treatment group in comparison with the placebo group

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

250

Conditions

Hypertensive Disease Deficiency of Vitamin D3

Interventions

Vitamin D3DIETARY_SUPPLEMENT

daily dosage of 50 µg Vitamin D3 for 8 weeks

PlaceboDIETARY_SUPPLEMENT

daily intake of placebo

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * human volunteers with mild hypertension Exclusion Criteria: * use of antihypertensive medication * use of vitamin d or calcium supplements * known renal, inflammatory or malignant diseases * hypercalcemia or hypercalciuria * participation in other clinical studies * use of tanning booths during the study

Outcomes

Primary Outcomes

blood pressure

major outcome variable is the decrease oy systolic blood pressure in the treatment group in comparison with the placebo group.

Time frame: after 8 weeks of supplementation

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.