A Longitudinal Study in 1st Degree Relatives of Parkinson's Disease (PD) Patients

Tel-Aviv Sourasky Medical Center100 enrolled

Overview

This is a longitudinal study in healthy 1st degree relatives of patients with Parkinson's Disease (PD) carriers of a genetic mutation in genes that are known to increase the risk for PD. The purpose of this study is to explore the association between genetic mutations in the known genes and early preclinical symptoms such as motor, sensory, autonomic, behavioral and cognitive functions.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Parkinson's Disease

Interventions

neurological examinationOTHER

motor and cognitive functions

Eligibility

Sex: ALLMin age: 35 YearsMax age: 85 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy 1ST degree relatives of PD patients with known genotype that participated in an earlier genetic study at the sourasky medical center. Exclusion Criteria: * subjects with cognitive decline by the parameters defined in DSM- IV * subjects with psychiatric disorder * subjects unable to sign a consent form

Locations (1)

Tel Aviv Sourasky Medical Center

Tel Aviv, Israel

Central Contacts

Anat Mirelman, PhD

CONTACT

972-3-6974958 anatmi@tasmc.health.gov.il

Data from ClinicalTrials.gov

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