Comparing an Automated to a Conventional Sepsis Clinical Prediction Rule

Beth Israel Deaconess Medical Center

Overview

The investigators will conduct a prospective cohort study to compare an automated sepsis severity score to a conventional clinical prediction rule to risk stratify patients admitted from the emergency department (ED) with suspected infection for 28 day in-hospital mortality.

Study Type

OBSERVATIONAL

Conditions

Sepsis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All consecutive adult (age 18 or older) Emergency Department (ED) patients during the study period that have been admitted from the ED and identified by the treating clinician to have a suspected infection at the time of ED disposition will comprise our study population. Exclusion Criteria: * No patients will be excluded from the study.

Locations (1)

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Outcomes

Primary Outcomes

28 day in-hospital mortality

The primary endpoint is the AUC of a model to predict 28 day all cause in-hospital mortality. Patients discharged or transferred to another hospital before 28 days will be assumed to be alive at 28 days.

Secondary Outcomes

ICU Admission

The secondary endpoint is ICU admission from the ED or within 24 hours from the floor.

Data from ClinicalTrials.gov

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