Inspiratory Resistive Loading and Diaphragm Fatigue

KU Leuven20 enrolled

Overview

The aim of the study is to clarify whether specific loading of the inspiratory muscles induces contractile fatigue of the diaphragm muscle in healthy individuals and individuals with recurrent low back pain.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Diaphragm Fatigue Healthy Low Back Pain

Eligibility

Sex: ALLMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria individuals with low back pain: * Age: 18-35 years old * At least 1 year of low back pain with/without referred pain in buttock/thigh * At least 3 episodes of disabling low back pain * At least a score of 20% on the Oswestry Disability Index * Willingness to sign the informed consent Inclusion Criteria healthy individuals: * Age: 18-35 years old * No history of low back pain * A score of 0% on the Oswestry Disability Index * Willingness to sign the informed consent Exclusion Criteria: * History of major trauma and/or major orthopedic surgery of the spine, the pelvis or the lower quadrant * One of the following conditions: Parkinson, multiple sclerosis, stroke, history of vestibular disorder, respiratory disease, pregnancy * Radicular symptoms * Not Dutch-speaking * Strong opioids * Neck pain * Smoking history

Locations (1)

Katholieke Universiteit Leuven

Leuven, Belgium

Outcomes

Primary Outcomes

transdiaphragmatic pressure

transdiaphragmatic pressure measurement in response to bilateral anterior magnetic phrenic nerve stimulation before and after an inspiratory resistive loading protocol

Time frame: 18 months

Data from ClinicalTrials.gov

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