The purpose of this study is to investigate the possible effect of hinge location on corneal sensation and dry eye syndrome after laser in situ keratomileusis (LASIK).
Dry eye symptoms are a frequent postoperative complication of laser in situ keratomileusis (LASIK). Although estimates of the incidence of dry eye syndrome vary widely, from 3% to 59%, almost all patients will have transient dry eye during the immediate postoperative period.Because of the variability in corneal innervation patterns, altering flap characteristics in LASIK may affect postoperative corneal sensation and dry-eye disease. Some studies have reported that postoperative corneal sensation may be higher and recovery faster in eyes with horizontal flaps (nasal- or temporal-hinge) than in eyes with vertical flaps (superior- hinge). However, some other studies have not established an association between corneal sensation and hinge position. This study reviewed the published literature and performed a meta-analysis aimed to investigate the effects of hinge location on corneal sensation and dry-eye symptoms after LASIK.
Study Type
OBSERVATIONAL
Enrollment
400
Wenzhou Medical College
Wenzhou, Zhejiang, China
Corneal sensitivity
Change of corneal sensitivity by using the Cochet-Bonnet esthesiometer,we chose to analyze results at 1 week and 1-, 3-, 6-month postoperatively.
Time frame: 6 months
Tear break-up time
Change of tear break-up time at 1 week and 1-, 3-, 6-month postoperatively
Time frame: 6 months
Schirmer's I test
Change of Schirmer's I score at 1 week and 1-, 3-, 6-month postoperatively
Time frame: 6 months
Corneal fluorescein staining
Time frame: 6 months
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