This study is initiated to investigate the effect of infant formulas with added specific prebiotic oligosaccharides on the reduction of specific potential pathogens and/or toxins.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
TRIPLE
Regular non-hydrolysed cow's milk with added prebiotic oligosaccharides mixture I
Regular non-hydrolysed cow's milk with added prebiotic oligosaccharides mixture II
Regular non-hydrolysed cow's milk with the same composition as the Investigational Formulas but without supplementation of prebiotic oligosaccharides
King Chulalongkorn Memorial Hospital
Bangkok, Thailand
Phramongkutklao Hospital
Bangkok, Thailand
Gut microbiota composition and its metabolic activity
* Gut microbiota composition: count and/or proportion and/or prevalence of group/genus/species of bacteria in the gut * Metabolic activity of the gut microbiota: pH, SCFA, lactate
Time frame: Week 6
Gastrointestinal symptoms (incidence and severity)
Time frame: Week 1, Week 3, Week 6, Week 8
Anthropometry
Time frame: Week 1, Week 3, Week 6, Week 8
Number, type and severity of (serious) adverse events
Time frame: Week 1, Week 3, Week 6, Week 8
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