a Prospective Study on the Efficacy of Magnifying Endoscopy With Narrow-band Imaging in Diagnosing Gastric Lesions

Xiaobo Li146 enrolled

Overview

Magnifying endoscopy with narrow-band imaging (ME-NBI) can emphasize surface pattern and microvascular architecture of the gastric mucosa.However,the usefulness and criteria of NBI for differential diagnosis among early gastric cancers (EGC) have not been fully established.The study is based on the hypothesis: 1. ME-NBI is useful in distinguishing EGC from other gastric lesions 2. ME-NBI is useful in further differential diagnosis among EGCs.

Study Type

OBSERVATIONAL

Enrollment

146

Conditions

Stomach Neoplasms

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * patients with gastric lesions which were detected by conventional screening endoscopy and suspected of early malignancy. Exclusion Criteria: * advanced gastric cancer or any other malignancy; * patients under unsuitable conditions for examination or treatment, such as acute upper gastrointestinal bleeding, noncorrectable coagulopathy, severe systemic disease, etc; * inability to provide informed consent; * inability to provide histology of resected specimens after endoscopic treatment or surgery.

Outcomes

Primary Outcomes

diagnosis accuracy of ME-NBI

ME-NBI diagnosis was made during real-time endoscopy procedure and reviewed in two weeks after ME-NBI examination. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of ME-NBI diagnosis compared with histology were measured.

Time frame: in 2 weeks after ME-NBI examination

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.