The Beneficial Role of Percutaneous Coronary Intervention Over Optimal Medical Therapy in Elderly Patients With Coronary Artery Disease

Inclusion Criteria: 1. Patients with CAD and those in whom initial CCS class I to III angina or Braunwald classification less than IIB 2. Patients with age 75 years or older 3. Patients receiving OMT (one or two anti-platelet agents, beta-blockers, calcium channel blockers, nitrates, angiotensin converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs), and statin) 4. Patients with stenosis of at least 70% in at least one proximal epicardial coronary artery or objective evidence of myocardial ischemia (substantial changes in ST-segment depression or T-wave inversion on the resting electrocardiogram or inducible ischemia with either exercise or pharmacologic vasodilator stress) 5. Patients with signed informed consent Exclusion Criteria: 1. Patients with persistence of CCS IV angina 2. Resting chest pain (≥ Braunwald classification IIB) 3. Patients who experienced a markedly positive stress test (substantial ST- segment depression or hypotensive response during stage 1 of the Bruce protocol) 4. Patients with age 85 years or older 5. Patients with refractory CHF or cardiogenic shock 6. Patients with an EF of less than 30% 7. Patients who have received revascularization within the previous 6 months 8. Patients with coronary anatomy not suitable for PCI 9. Life expectancy ≤ 2 year