Diurnal Variation of Exogenous Peptides (Endogenous Insulin Jurgita II)

Inclusion Criteria: * Subjects with type 2 diabetes mellitus * Insulin-naive patients * HbA1C \< 9% * Women and men \>= 35 and \<= 75 years old * BMI 25-42 kg/m2, both values are included Exclusion Criteria: * Suspected or known allergy to the trial drug or similar medications * Treatment with hte drugs that after Investigator judgment could potentially interfere with plasma glucose levels * Heart: Unstable angina pectoris, acute myocardial infarction within the last 12 months * Severe uncontrolled hypertension with blood pressure in lying position \> 180/110 mmHg * Impaired liver function with liver parameters more than 2 times above the upper normal limit according to the local laboratory * Impaired kidney function with eGFR \< 50 ml/min according to the local laboratory * Pregnancy, lactation or desire for pregnancy in the study period and for women in childbearing age without adequate contraception-adequate contraception is: sterilisation, hysterectomy or current use of contraceptive pills, coil, gestagen depot injection, subdermal implantation, hormonal vaginal ring and transdermal depot patch.