The purpose of this study is to determine whether cardiac resynchronization therapy (CRT) is superior to interventricular right ventricle (RV) septal pacing in respect of reverse remodeling (LV ESD) and morbidity in patients with less preserved (less than 45%) ejection fraction (EF), persistent/permanent atrial fibrillation (AF) who successfully received atrioventricular (AV) junction ablation ablation (100% pacemaker dependency)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
11
RV lead of CRT system is implanted into the middle part of interventricular septum
RV lead is implanted into the middle part of interventricular septum
Almazov Federal Heart, Blood and Endocrinology Centre
Saint Petersburg, Russia
Left Ventricle End-Systolic Volume (LV ESV)
Time frame: 12 months
Rate of cardiovascular events (hospitalization for worsening heart failure)
Time frame: 12 month
Changes in Quality of Life (measured by Minnesota Living with Heart Failure Questionnaire)
Time frame: 12 months
Changes in NYHA functional class measured by peak V O2 oxygen consumption and distance of 6-minute walk test
Time frame: 12 months
Echocardiographic indexes of LV remodeling
Time frame: 12 months
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