Efficacy of Prokinetics With Split Dose of PEG in Morning Colonoscopic Bowel Preparation

Inje University152 enrolled

Overview

In bowel preparation using split dose PEG, various adjuncts to colonic cleansing were proposed to improve colonic preparation cleansing. Prokinetics, as an adjunct, was included in a few studies. The investigators study was to show that sufficient dosage of prokinetics added to split dose of PEG improves the state of bowel preparation.

This was a randomized, prospective, endoscopist-blinded clinical trial in which the efficacy of prokinetics coadministrated with split dose PEG on the bowel cleansing was inspected. Endoscopists, who were blinded to the study group of the patient, immediately completed the Ottawa scale and the fluidity scale after procedure

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

152

Conditions

Colonoscopy Bowel Preparation

Interventions

itoprideDRUG

itopride, 10mg, twice per day, for 1 day

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient who are scheduled for colonoscopy Exclusion Criteria: * pregnancy, * breast feeding, * known or suspected bowel obstruction, and * known allergy to PEG or Itopride , * presence of severe illness(renal failure, congestive heart failure, liver failure,), and * refusal of consent to participate in the study

Locations (1)

Haeundae Paik Hospital, Inje University School of Medicine

Busan, South Korea

Outcomes

Primary Outcomes

bowel cleaning quality according to Ottawa scale scores

Time frame: 3 months

Secondary Outcomes

procedure time and polyp detection rate

cecal intubation time, polyp detection rate, degree of patient discomfort

Time frame: 3 months

Data from ClinicalTrials.gov

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