The Effect of Dexmedetomidine on the Emergence Agitation in Nasal Surgery

Severance Hospital100 enrolled

Overview

The investigators examined the effect of dexmedetomidine on the emergence agitation and postoperative quality of recovery in nasal surgery

Emergence agitation during the immediate postanesthetic period is common. It may lead to serious consequences for the patient, such as injury, increased pain, hemorrhage, self-extubation, and removal of catheters. Emergence agitation is common in ENT surgery. The aim of this study is to evaluate the effect of dexmedetomidine on the emergence agitation and postoperative quality of recovery in adult patients undergoing nasal surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

100

Conditions

Airway Extubation

Interventions

DexmedetomidineDRUG

Dexmedetomidine(4㎍/mL) : 0.4㎍/kg/hr infusion until extubation

Normal saline 0.9%DRUG

Normal saline(guess as 4㎍/mL) : 0.4㎍/kg/hr infusion until extubation

Eligibility

Sex: ALLMin age: 20 YearsMax age: 59 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age ≥ 20, * ASA class I and II, * nasal surgery Exclusion Criteria: * bradycardia (\< 45 bpm), * heart block, * liver failure, * renal failure, * uncontrolled hypertension, * body mass index ≥ 30 kg/m2

Locations (1)

Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine

Seoul, South Korea

Outcomes

Primary Outcomes

Emergence agitation

Time frame: 20min

Secondary Outcomes

Postoperative quality of recovery

Time frame: 1 day

Data from ClinicalTrials.gov

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