LOXL1 Polymorphism in Pseudoexfoliation Syndrome

Samsung Medical Center60 enrolled

Overview

To evaluate the association profiles of the lysyl oxidase-like 1 gene polymorphisms with pseudoexfoliation syndrome in the Korean population, Genotypes of lysyl oxidase-like 1 gene were analyzed by direct sequencing.

To evaluate the association profiles of the lysyl oxidase-like 1 gene polymorphisms with pseudoexfoliation syndrome in the Korean population, peripheral blood sampling will be done from the patients with pseudoexfoliation. And genotypes of the three single nucleotide polymorphisms of lysyl oxidase-like 1 gene , rs1048661, rs3825942, rs2165241 were analyzed by direct sequencing.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pseudoexfoliation Syndrome

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of Pseudoexfoliation Exclusion Criteria: * medical condition that peripheral blood sampling cannot be done

Locations (1)

Samsung medical center

Seoul, South Korea

RECRUITING

Outcomes

Primary Outcomes

Genotypes of the three single nucleotide polymorphisms of LOXL1 (rs1048661, rs3825942, rs2165241)

Genotypes of the three single nucleotide polymorphisms of LOXL1 were analyzed by direct sequencing, after obtained from the peripheral blood sampling from patients.

Time frame: about 1 year (when all patients were recruited)

Central Contacts

Changwon Kee, M.D., Ph.D.

CONTACT

82-2-3410-3564 ckee@skku.edu

Data from ClinicalTrials.gov

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