The purpose of the study is to examine how a dietary fiber affects metabolism in healthy overweight and obese adults. The fiber will be added to foods that participants will consume for two, three-week periods. The fiber will be given in two doses -- 15 g per day during one period, and 30 g per day in the other. In another three-week period, they will consume the same foods, but with no fiber added. Major outcomes will include fermentability of the fiber, as assessed by measurement of breath hydrogen, as well as shifts in fecal bacteria. The caloric value of the fiber will be determined and metabolic measures related to blood glucose control and inflammation will also be taken.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
20
Dietary fiber will be added to study foods
USDA, ARS, Western Human Nutrition Research Center
Davis, California, United States
Metabolizable energy
Urine and feces will be collected for 7 days at the end of each treatment period to allow for assessment of metabolizable energy
Time frame: 7 days, 3 times
Fermentability
Breath hydrogen will be measured hourly, over eight hours at the end of each treatment period
Time frame: One, eight-hr day, three times
Fecal microbiota
Fecal samples will be collected for 7 days at the end of each treatment period and for two days during washout periods
Time frame: 2 days, three times, and 7 days, three times
Blood glucose
An indwelling catheter will be placed and blood samples will be drawn over the course of an eight-hour period, at the end of each treatment period
Time frame: For eight hours, three times
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.