Antro-pyloro-duodenal Motility in Idiopathic Gastroparesis

N/ACompletedNCT01519180

University Hospital, Rouen32 enrolled

Overview

Impaired gastric emptying may cause dyspeptic symptoms including nausea, vomiting and even nutritionnal impairment. Delay in gastric emptying may result from antro-pyloro-duodenal motility impairement.

The aim of this study is therefore to measure antro-pyloro-duodenal motor activity in patients with idiopathic gastroparesis.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Gastroparesis

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Idiopathic gastroparesis or healthy volunteers * Idiopathic gastroparesis must have delayed gastric emptying shown using C13 breath test Exclusion Criteria: * Diabetic or post-surgical gastroparesis * Treatment modifying GI motility (prokinetics, opioids...) * Parkinson or neurologic disease * Evoluting inflammatory process or neoplasia * Treatment modifying coagulation * Patients not affiliated to the French healthcare insurance

Locations (1)

Service de Physiologie

Rouen, Haute Normandie, France

Outcomes

Primary Outcomes

antro-pyloro-duodenal pressure

the main outcome is the pressure measured using pressure sensors within the antrum, the pylorus, and the first part of the duodenum. This will be measured during 3h fast. Pressures measured in the antrum, the pylorus, and the duodenum wiil be compared between healthy volunteers and gastroparetic patients

Time frame: 3h

Data from ClinicalTrials.gov

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