Assessment of NSAID-treated Patients Adherence to Co-prescribed Proton Pump Inhibitor (PPI)

N/ACompletedNCT01519375

AstraZeneca102 enrolled

Overview

The primary objective of this cross-sectional observational real life study is to investigate the patient reported adherence to PPI, when prescribed as prevention of NSAID associated GI Ulcers to patients prescribed a NSAID. Patients included have Osteoarthritis, Rheumatoid Arthritis or Ankylosing Spondylitis. Adherence will be assessed by patient questionnaires.

Cross-sectional, observational Real Life study on NSAIDs treated patients with Osteoarthritis, Rheumatoid Arthritis and Ankylosing Spondylitis: Assessment of patient adherence to PPI treatment

Study Type

OBSERVATIONAL

Enrollment

102

Conditions

Osteoarthritis Rheumatoid Arthritis Ankylosing Spondylitis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Confirmed diagnosis (documented in the medical record) of OA, RA or AS * Prescription of oral NSAID treatment for OA, RA or AS, where low dose is not sufficient * Prescription of PPI for prevention of NSAID associated GI ulcers, with instruction to take PPI same day as when taking NSAID. Exclusion Criteria: * Participating in any clinical trial involving PPI or NSAID * Patients prescribed PPI as acute treatment of GI events or symptoms within 8 weeks * Inability to complete PROs

Locations (8)

Research Site

Kristianstad, Sweden

Research Site

Kristinehamn, Sweden

Research Site

Limhamn, Sweden

Research Site

Partille, Sweden

Outcomes

Primary Outcomes

Patient reported adherence to PPI treatment on actual days of NSAID treatment.

Time frame: 7 days

Secondary Outcomes

Proportion of patients with reported adherence ≤ 80%.

Time frame: 7 days

Patient adherence to prescribed ASA treatment.

Time frame: 7 days

Data from ClinicalTrials.gov

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