Noninvasive brain stimulations (NIBS) will be used in chronic stroke patients to improve motor learning. Functional magnetic resonance imaging will be used to evaluate the mechanisms underlying motor learning in healthy volunteers and in chronic stroke patients.
transcranial direct current stimulation will be used for NIBS
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
100
tdcs (ELDITH, Neuroconn, Ilmenau, Germany)
TMS (The Magstim Company Ltd, UK) Magstim 200² with a figure-of-eight coil was used to determine the hot spot eliciting consistent movements in the contralateral hand
Department of Neurology, CHU Mont-Godinne
Yvoir, Namur, Belgium
Motor learning improvement with tDCS
performance on a motor skill learning task and on different commonly used task (Purdue Pegboard, hand dynamometer, pinch dynamometer, 9-HPT ,...) were measured to explore the impact of tDCS on these parameters
Time frame: Improvement on motor learning were recorded from baseline to 4 weeks after the intervention
Neuroimaging
Does cerebral mechanisms underlying motor learning differ from healthy subject to stroke patients?
Time frame: before motor learning, during motor learning and after (immediately, 30,60min) motor learning (with or without tDCS)
Neurophysiological outcome measure
measure of brain excitability and connectivity with TMS (single and paired pulse)
Time frame: start of session 5min before motor learning, just at the end of the motor learning, after 30 min of motor learning, after 60 min of motor learning, Recall test at 1,2,3,4 weeks after the day of intervention (with or without tDCS)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.