The Effect of Fat on Vitamin D Absorption

N/ACompletedNCT01519986

Federal University of Rio Grande do Sul64 enrolled

Overview

The purpose of this study is to evaluate the absorption of dietary supplement of vitamin D3 (cholecalciferol), through the variation of 25 (OH) D levels, as the fat content of the meal associated with the administration of the supplement.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

DOUBLE

Enrollment

Conditions

Vitamin D Deficiency

Interventions

Vitamin D3DIETARY_SUPPLEMENT

Supplement of vitamin D3

PlaceboDIETARY_SUPPLEMENT

Placebo

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Residents of the hospital clinics of Porto Alegre Exclusion Criteria: * Don't drink milk * Obesity * Malnutrition * Liver disease * Kidney disease or diabetes * Use of dietary supplements containing calcium and vitamin D * Medications * Anticonvulsants * Barbiturates, or steroids. * Having performed a journey the last four months to locations near the Earth's equatorial plane, due to sun exposure that may have occurred during this period, or vacations planned during the study period.

Outcomes

Primary Outcomes

Change from baseline in serum 25(OH)D at 14 day after intervention

25(OH)D response to supplemental vitamin D3

Time frame: Change from baseline in serum 25(OH)D at 14 days

Secondary Outcomes

Change from baseline in Parathyroid hormone at 14 days after intervention

Parathyroid hormone response to supplemental vitamin D3

Time frame: Change from baseline in Parathyroid hormone at 14 days

Data from ClinicalTrials.gov

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