The primary objective of this study is to determine if broccoli sprouts (BS) improves airway inflammatory, oxidative stress (OS), and symptoms among asthmatic adults with aeroallergen sensitization. The study is a double-blind, placebo-controlled, randomized trial to compare BS to placebo in 40 adults with asthma. 40 adults (age 18-50) who meet these eligibility criteria will be randomized to receive either: (a) BS or (b) placebo (alfalfa sprouts). Subjects will eat a sprouts sandwich daily for three days, and then undergo repeat measurement of outcomes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
51
100g of either broccoli or alfalfa sprouts will be eaten daily in a sandwich or wrap form.
Alfalfa Sprouts
Johns Hopkins Hospital
Baltimore, Maryland, United States
Exhaled Nitric Oxide Concentrations
exhaled nitric oxide concentrations
Time frame: at 3 days
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