This trial is conducted in Europe. The aim of this trial is to compare two formulations of biphasic insulin aspart 70 and characterise the pharmacokinetics of biphasic insulin aspart 50 and biphasic insulin aspart 70 in healthy male subjects.
Each subject participated in three treatment periods, and were randomly assigned to each of the six treatment sequences in varying order
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
24
A single dose administrated subcutaneously (s.c., under the skin)
A single dose administrated subcutaneously (s.c., under the skin)
A single dose administrated subcutaneously (s.c., under the skin)
Novo Nordisk Investigational Site
Leeds, United Kingdom
Area under the insulin aspart curve in the interval from 0-24 hours
Cmax, maximum insulin aspart concentration
tmax, the time to maximum insulin aspart concentration
t½, terminal half-life
Cmin, minimum glucose concentration
tmin, time to minimum concentration
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