Cytoreduction and Intraperitoneal Chemotherapy Versus Systemic Chemotherapy in Colorectal Peritoneal Carcinomatosis

Inclusion Criteria: * Metastatic disease to the peritoneum from colon or rectum (at least two isolated sites of disease) * verified primary tumor of adenocarcinoma of the colon or rectum * Potential resectability as judged by the treating surgeon * Patient is available for follow-up according to the study protocol * Signed informed consent Exclusion Criteria: * Extraabdominal metastases or liver metastases * Paraaortic or other inoperable lymph node metastases * Clear indication for surgery only (such as obstruction, bleeding or peritonitis) * Prior treatment of either arm in the study * Clinical or histopathological diagnosis of Peritoneal Pseudomyxoma * Age \> 80 * Contraindications for chemotherapy * Pregnancy or breastfeeding * Ongoing infection