The aim of our study was to evaluate the significance of monitoring anesthetic depth for the conduct of anesthesia and the early postoperative period in patients subjected to surgical correction of combined valvular disorders.
Our aim was to evaluate the effect of monitoring anesthetic depth on duration of postoperative mechanical ventilation and ICU stay after surgical correction of combined valvular disorders.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
28
intraoperative maintenance of anesthesia with propofol under control of cerebral state index at 40-60 points
intraoperative maintenance of anesthesia with propofol according to recommendations of the manufacturer
duration of postoperative mechanical ventilation
Criteria for termination of postoperative respiratory support were the following: patient able to cooperate; adequate muscular tone; SpO2 \> 95% with FiO2 0.5; PaCO2 \< 45 mm Hg; postoperative bleeding rate \< 50 mL hr-1; stable hemodynamics without inotropic/vasopressor support; body temperature of \> 35 °C. Temporary pacing was not regarded as a contraindication for tracheal extubation.
Time frame: 24 hours postoperatively
length of ICU stay
The time until 'fit for ICU discharge' criteria as well as the actual length of the ICU stay were registered. The 'fit for ICU discharge' criteria included the following: fully oriented patient, SaO2 \> 90% on room air, no episodes of severe arrhythmias, bleeding \< 50 mL hr-1, diuresis \> 0.5 mL kg-1 hr-1, no need for inotropic/vasopressor support and no signs of ischemia on ECG.
Time frame: 7 days postoperatively
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