The primary purpose of this study is to determine whether the hepatitis C virus continues to remain unable to be detected in subjects who were previously treated with BMS-914143 and achieved sustained virologic response
Study Type
OBSERVATIONAL
Enrollment
218
Observational study - No Intervention \[subjects were previously treated with Peginterferon Lambda-1a (BMS-914143)\]
Durability of virologic response (time to loss of virologic response)
Durability of virologic response as assessed by the time to loss of virologic response in subjects treated in a previous study with BMS-914143 who have HCV RNA less than the limit of quantitation of the assay (\< LOQ) at the completion of the required post-treatment follow-up in the previous study. Loss of virologic response assessed using HCV RNA at 24-week intervals
Time frame: 24 week intervals from end of treatment in parent study up to 144 weeks
Long-term progression of liver disease
Long-term progression of liver disease as measured by laboratory indicators of hepatic status and function, all-cause mortality and liver related mortality in subjects previously treated with BMS-914143 who have HCV RNA \< LOQ at the completion of the required post-treatment follow-up in the parent study
Time frame: 24 week intervals up to 144 weeks
Duration of persistence of anti-Lambda antibodies in subjects who are positive for anti-Lambda antibodies at end of treatment in the parent study
Time frame: 24 week intervals up to 144 weeks
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