The aim of this trial is to assess the effect of hydrolyzed egg orally administered on oral tolerance induction to egg in children allergic to egg as compared to a placebo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
29
Daily dose of HA egg or placebo for 6 months
University of Athens
Athens, Greece
University Hospital of Padua
Padua, Italy
Hochgebirgsklinik Davos
Wolfgang, Switzerland
positive or negative result (objective and subjective symptoms) of a challenge test with egg
Time frame: 6 months
compliance (product taken)
Time frame: 6 months
skin prick test (sensitization to egg; size of wheal and flare)
Time frame: 6 months
Immunological parameters: total and specific IgE and IgG4, cytokines, basophil activation
Time frame: 6 months
Morbidity / Adverse Events
Time frame: 6 months
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