Pulsed Dye Laser (PDL) vs. Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness

Northwestern University16 enrolled

Overview

The primary objective of this study is to compare the efficacy of PDL and the 1064-nm Nd:YAG laser in the treatment of facial redness.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Rosacea

Interventions

Pulse Dye Laser/YAG laserPROCEDURE

This study involves treatments with two types of lasers, Pulsed dye lasers (PDL) and the 1064 nm Nd: YAG. Both lasers are FDA approved to treat vascularities in the skin.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy patients 18-55 years of age with erythematotelangiectatic rosacea (as verified by the the PI). * Subjects who are willing to provide informed consent for participation in the study. Exclusion Criteria: * Pregnant or lactating individuals * Subjects who are unable to understand the protocol or to give informed consent. * Subjects who have a known history of photosensitive conditions (e.g. Systemic lupus, polymorphous light eruption) * Subjects who have facial telangiectasia of diameter greater than 2 mm. * Subject who have significant (as determined by the PI) acute inflammatory papules, pustules, and vesicle involving the central face.

Locations (1)

Northwestern University Feinberg School of Medicine, Department of Dermatology

Chicago, Illinois, United States

Outcomes

Primary Outcomes

Rating on global improvement scale

Non-treating dermatologists will rate each side of the face using a global improvement scale to evaluate the effectiveness of the two treatments.

Time frame: four months

Spectrophotometer measurement

Spectrophotometer measurement as the percent resolution on each follow up visit compared to baseline visit

Time frame: four months

Secondary Outcomes

Patient satisfaction

Patients will record satisfaction on the questionnaires provided

Time frame: four months

Recorded discomfort

Subjects will record discomfort using a 10-point scale

Time frame: four months

Adverse events

Any adverse events will be recorded

Time frame: four months

Data from ClinicalTrials.gov

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