Oral Sodium Blood Pressure in Normal Weight, Overweight and Obese Volunteers

Poitiers University Hospital51 enrolled

Overview

The primary objective of this study is to analyze the sensitivity of blood pressure to oral salt intake. Matched male and female participants will be selected as normal weight, overweight, and obese. Participating subjects will have a first visit with blood pressure measurement and a blood sample. In two consecutive phases of one week, subjects will receive 12 pills of sodium (6 grams) or corresponding placebo. Blood pressure will be measured at the end of each phase.

Study Type

INTERVENTIONAL

Enrollment

Conditions

Obesity

Interventions

sodium chlorideOTHER

sodium chloride 500mg

Methylcellulose crystallineOTHER

Methylcellulose 37 ml

Eligibility

Sex: ALLMin age: 6 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Informed consent * Age 18-45 for adults and 6-8 for children Exclusion Criteria: * African ethnicity (known to affect blood pressure sensitivity to salt) * Chronic condition affecting blood pressure * Diabetes (known to affect blood pressure sensitivity to salt) * Hypertension

Locations (1)

Poitiers University Hospital

Poitiers, France

Data from ClinicalTrials.gov

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