RATIONALE: A stellate ganglion nerve block may help relieve symptoms of post-traumatic stress disorder (PTSD). PURPOSE: This pilot clinical trial is studying the efficacy of a stellate ganglion nerve block in veterans to reduce the symptoms of PTSD in relatively long-standing (Vietnam era) induced or relatively recently induced PTSD (from deployment in Afghanistan or Iraq as part of Operations Enduring Freedom (OEF), Iraqi Freedom (OIF), and New Dawn (OND).
Objectives: 1. Stellate ganglion blocks will be performed in a small sample (n = 12) of the local patient population that suffers from PTSD in order to replicate other preliminary findings. 2. The parameters that lead to a successful treatment response will be evaluated by comparing and contrasting the results obtained in younger (n=6) OEF/OIF generation veterans versus older (n=6) Vietnam generation veterans. 3. The individual difference variables that might lead to successful treatment responses will be studied by obtaining correlative measures of psychological and psychometric data and responses to standardized tests. Research Design: This is an open label unblinded clinical pilot case series study to determine the efficacy of stellate ganglion blockade for relief of PTSD symptoms in the Long Beach VA healthcare population.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
12
Local anesthesia applied to the stellate ganglion in the neck
VA Long Beach Healthcare system
Long Beach, California, United States
RECRUITINGDifference in CAPS score activity
Time frame: Baseline and weeks 1, 4, 12 and 26
Depression scale
Time frame: Baseline and weeks 1, 4, 12 and 26
Anxiety scale
Time frame: Baseline and weeks 1, 4, 12 and 26
Quality of life scale
Time frame: Baseline and weeks 1, 4, 12 and 26
Biophysical responses
Time frame: Baseline and weeks 1, 4, 12 and 26
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