A Comparison Study of the Tensile Strength of Sutures Used in Dermatologic Surgery on the Day of Suture Removal, Following Wound Care With Two Different Products

University of Miami40 enrolled

Overview

Sutures are an integral part of surgery and available materials are diverse, as are the options for post-procedure care. Both saline and hydrogen peroxide are commonly used cleansing agents. This study aims to compare the effect of saline and hydrogen peroxide on the tensile strength of 4-0 nylon sutures following removal from a cutaneous surgical wound.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Sutured Wounds

Interventions

Hydrogen peroxideOTHER

Once daily topical application of 3% hydrogen peroxide using a cotton-tipped applicator

SalineOTHER

Once daily topical application of normal saline, using a cotton-tipped applicator

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Subject is willing to comply with the informed consent procedures * Subject's wound is on the body or scalp * Subject will be able to come to the clinic for suture removal on day 14 Exclusion Criteria: * Subject is less than 18 years of age * Subject's wound was not closed with 4-0 nylon sutures * Subject's wound is on the face * Subject plans to apply other topicals to the area under study * Subject's suture is removed before or after day 14

Locations (1)

University of Miami Hospital and Clinics/Sylvester Comprehensive Cancer Center

Miami, Florida, United States

Outcomes

Primary Outcomes

Tensile strength of 4-0 nylon sutures

The tensile strength was defined as the force required to break the suture, with breaking strength as the maximum strength that a material can withstand when subjected to an applied load, without taking into consideration the cross sectional area. The strength of the sutures was measured using a tensometer.

Time frame: 14 days

Data from ClinicalTrials.gov

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