Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis

Universitätsmedizin Mannheim250 enrolled

Overview

During the past years many investigators have focused on the immunological changes in sepsis disease, and great attention has been paid to the development of practicable means of immunomonitoring. Little is known about diagnostic and prognostic vascular biomarkers during the time course of patients with sepsis.

Primary Outcome Measures: New diagnostic and prognostic markers for septic patients Estimated Enrollment: 300 patients Study Start Date: January 2012 Estimated Study Completion Date: open Estimated Primary Completion Date: open Intervention Details: Procedure: vein puncture comparison of different inflammatory markers in the blood of septic patients

Study Type

OBSERVATIONAL

Enrollment

250

Conditions

Sepsis

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * SIRS-Criteria * Proven Infection * One sepsis-induced organ-failure * Adults \< 18 years old Exclusion Criteria: * Anemia * Pregnancy * Blood donor in the last 3 month

Locations (1)

University Medical Centre Mannheim

Mannheim, Baden-Wurttemberg, Germany

Data from ClinicalTrials.gov

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