Safety and Efficacy Evaluation of Topical AL-60371 Otic Suspension, 0.3% in the Treatment of Acute Otitis Externa

Inclusion Criteria: * At least 6 months of age. * Clinical diagnosis of acute otitis externa (AOE) based on clinical observation and of presumed bacterial origin in at least one ear. * Combined numerical score of ≥4 in at least one affected ear at the Day 1 exam for tenderness, erythema, and edema. * Agree to refrain from water immersion of the ears during the conduct of the entire study. * Other protocol-defined inclusion criteria may apply. Exclusion Criteria: * Duration of signs or symptoms of AOE greater than 28 days in the affected ear(s) as reported by patient or parent/guardian. * Presence of a tympanostomy tube or perforated tympanic membrane in the affected ear(s). * Clinically diagnosed otic disease other than AOE (eg, malignant otitis externa) in the affected ear(s). * Known or suspected ear infection of yeast, fungal or mycobacterial origin in the affected ear(s). * Prior otologic surgery within 6 months of study entry in the affected ear(s). * Known or suspected allergy or hypersensitivity to quinolones or other ingredients present in the medications to be used in the study. * Patients who use ear plugs, head phones or ear buds and are unwilling to discontinue their use during the study period. * Other protocol-defined exclusion criteria may apply.